{"product_id":"9780470027554","title":"Novartis Foundation Symposia","description":"\u003ch1\u003eNovartis Foundation Symposia\u003c\/h1\u003e\u003ch2\u003e\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eContributors:\u003c\/strong\u003e Bock, Gregory R.; Goode, Jamie A.\u003c\/p\u003e\u003cp\u003eThis book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections.  The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions. This will require innovative, interdisciplinary and collaborative strategies of a scale and complexity we are only now beginning to comprehend.  \u003c\/p\u003e\u003cp\u003eSpecific problems addressed include the following:\u003c\/p\u003e \u003cul type=\"disc\"\u003e \u003cli\u003eWhat kinds of information are we lacking to understand how the genome sequence specifies the differentiation and response of immune system cells, and system behaviour such as immunological memory and tolerance?\u003c\/li\u003e \u003cli\u003eWhich genome sequences and cellular circuits cause or prevent pathological immune responses to foreign pathogens, allergens or self-tissues?\u003c\/li\u003e \u003cli\u003eWhich host and pathogen genome sequences and cellular circuits explain the failure of sterilizing immune responses to sophisticated human pathogens such as the agents of tuberculosis, malaria, metazoan parasites and chronic viruses?\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eContaining contributions from a range of leading experts in the field, this book provides an important new perspective for clinical immunologists and basic researchers alike.\u003c\/p\u003e\u003ch3\u003eBook Details\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublisher:\u003c\/strong\u003e Wiley\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e 2007-04-16\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Hardcover\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eISBN-13:\u003c\/strong\u003e 9780470027554\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePages:\u003c\/strong\u003e 232\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44385463664780,"sku":"9780470027554","price":190.76,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470027554.jpg?v=1768945490","url":"https:\/\/lateknightbooks.com\/products\/9780470027554","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}