{"product_id":"9780470028421","title":"Multivariable Model - Building A Pragmatic Approach to Regression Anaylsis based on Fractional Polynomials for Modelling Continuous Variables","description":"\u003ch3\u003eWiley Series in Probability and Statistics\u003c\/h3\u003e\u003ch1\u003eMultivariable Model - Building\u003c\/h1\u003e\u003ch2\u003eA Pragmatic Approach to Regression Anaylsis based on Fractional Polynomials for Modelling Continuous Variables\u003c\/h2\u003e\u003ch3\u003ePatrick Royston | Willi Sauerbrei\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMathematics \/ Probability \u0026amp; Statistics \/ General\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eMultivariable regression models are of fundamental importance in all areas of science in which empirical data must be analyzed. This book proposes a systematic approach to building such models based on standard principles of statistical modeling. The main emphasis is on the fractional polynomial method for modeling the influence of continuous variables in a multivariable context, a topic for which there is no standard approach. Existing options range from very simple step functions to highly complex adaptive methods such as multivariate splines with many knots and penalisation. This new approach, developed in part by the authors over the last decade, is a compromise which promotes interpretable, comprehensible and transportable models.\u003c\/div\u003e\u003cdiv\u003e  \u003cb\u003ePatrick Royston\u003c\/b\u003e DSc, is a senior statistician and cancer clinical realist at the MRC Clinical Trials Unit, London, an honorary professor of statistics at University College London and a fellow of the Royal Statistical Society. he has authored many research papers in biostatistics, and has published over 150 articles in leading statistical journals. Patrick is an experienced statistical consultant, Stata programmer and software author.  \u003cp\u003e\u003cb\u003eWilli Sauerbrei\u003c\/b\u003e PhD, is a senior statistician and professor in medical biometry at the IMBI, University Medical Center Freiburg. He has authored many research papers in biostatistics and has published over 100 articles in leading statistical and clinical journals. He worked for more than two decades as an academic biostatistician and has extensive experience of cancer research, with a particular concern for breast cancer.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e21 July 2008\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470028421\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e328\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e24.32\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310453452940,"sku":"9780470028421","price":132.26,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470028421.jpg?v=1780157478","url":"https:\/\/lateknightbooks.com\/products\/9780470028421","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}