{"product_id":"9780470118795","title":"Combating the Threat of Pandemic Influenza Drug Discovery Approaches","description":"\u003ch1\u003eCombating the Threat of Pandemic Influenza\u003c\/h1\u003e\u003ch2\u003eDrug Discovery Approaches\u003c\/h2\u003e\u003ch3\u003ePaul F. Torrence\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Infectious Diseases\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eDrug discovery for influenza antivirals\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePriorities for combating pandemic influenza include rapid detection and identification, the quick administration of available drugs to treat the infection, the development of new antivirals, and the development of vaccines. Since lead-time may be required to produce an effective vaccine, antivirals would serve as a key first line of defense in containing an outbreak. Diverse antivirals, acting through different mechanisms, would help stay the development of resistant viruses. Thus, drug discovery for influenza antivirals is an important public health–related endeavor.\u003c\/p\u003e \u003cp\u003eWith chapters contributed by leading international specialists, this guide gets readers up to speed on the latest advances and technologies in diverse approaches to drug discovery, covering:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eExisting antivirals, including broadly effective anti-respiratory virus agents\u003c\/li\u003e \u003cli\u003eThe development of high-throughput screening assays\u003c\/li\u003e \u003cli\u003eIFN resistance\u003c\/li\u003e \u003cli\u003eThe development of nucleic acid–based antiviral drugs\u003c\/li\u003e \u003cli\u003eAntiviral RNAi strategies targeting influenza virus\u003c\/li\u003e \u003cli\u003eOther promising antiviral drug discovery strategies\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eCombating the Threat of Pandemic Influenza: Drug Discovery Approaches\u003c\/i\u003e consolidates the latest information on diverse approaches into one comprehensive resource. It is an invaluable, hands-on reference for researchers in medicinal chemistry, pharmaceutical chemistry, drug discovery, biochemistry, virology, microbiology, and public health.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e \u003cp\u003e\u003cb\u003ePaul F. Torrence\u003c\/b\u003e, PhD, joined the National Institutes of Health in 1969 and served as Chief of the section on Biomedical Chemistry at the National Institute of Diabetes and Digestive and Kidney Diseases from 1989–1999. From 1999–2007, he was a Professor of Chemistry and Biochemistry at Northern Arizona University where he taught organic, bioorganic, and medicinal chemistry, as well as drug discovery.Professor Torrence's research pursued drug discovery for the diseases of smallpox, HIV, West Nile Virus, and cancer with grant support from the National Institutes of Health, Department of Defense Congressionally Directed Medical Research Program, the U.S. Army Institute of Infectious Diseases, the Arizona Disease Control Research Commission, Arizona Proposition 301 funds, and Research Corporation. Presently he is Emeritus Professor of Chemistry and Biochemistry at Northern Arizona University.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e05 October 2007\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Interscience\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470118795\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e316\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e19.94\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44378418741388,"sku":"9780470118795","price":183.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470118795_b548a9f9-d052-487a-a6fc-87f9c4529124.jpg?v=1780139462","url":"https:\/\/lateknightbooks.com\/products\/9780470118795","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}