{"product_id":"9780470503485","title":"Forward-Time Population Genetics Simulations Methods, Implementation, and Applications","description":"\u003ch1\u003eForward-Time Population Genetics Simulations\u003c\/h1\u003e\u003ch2\u003eMethods, Implementation, and Applications\u003c\/h2\u003e\u003ch3\u003eBo Peng | Marek Kimmel | Christopher I. Amos\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Life Sciences \/ Genetics \u0026amp; Genomics\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eThe only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies  \u003cp\u003eThe rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. \u003ci\u003eForward-Time Population Genetics Simulations\u003c\/i\u003e presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators.\u003c\/p\u003e \u003cp\u003eThe book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eForward-Time Population Genetics Simulations\u003c\/i\u003e includes:\u003c\/p\u003e \u003cul\u003e \u003cli\u003e \u003cp\u003eAn overview of currently available forward-time simulation methods, their advantages, and shortcomings\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eAn overview and evaluation of currently available software\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eA simuPOP tutorial\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eApplications in population genetics\u003c\/p\u003e \u003c\/li\u003e \u003cli\u003e \u003cp\u003eApplications in genetic epidemiology, statistical genetics, and mapping complex human diseases\u003c\/p\u003e \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThe only book of its kind in the field today, \u003ci\u003eForward-Time Population Genetics Simulations\u003c\/i\u003e will appeal to researchers and students of population and statistical genetics.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cb\u003eBo Peng, PHD,\u003c\/b\u003e is an assistant professor in the Department of Genetics at The University of Texas MD Anderson Cancer Center. With his degrees in applied mathematics and biostatistics, he is applying advanced computational techniques such as parallel computation and large-scale simulations to research topics in population genetics, genetic epidemiology, and bioinformatics.  \u003cp\u003e\u003cb\u003eMarek Kimmel, PHD\u003c\/b\u003e, is Director of the Doctoral Program in Bioinformatics and Statistical Genetics and head of the Bioinformatics Group at Rice University. He holds joint appointments as Professor of Statistics at Rice University, Professor of Biostatistics and Applied Mathematics at MD Anderson Cancer Center, and Professor of Biometry at The University of Texas School of Public Health.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChristopher I. Amos, PHD\u003c\/b\u003e, is a professor in the Department of Genetics at The University of Texas MD Anderson Cancer Center. He also holds adjunct appointments at Rice University and in the Department of Epidemiology at The University of Texas School of Public Health.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e14 February 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Blackwell\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470503485\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e256\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e14.72\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44314971144332,"sku":"9780470503485","price":116.06,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470503485_c1818411-bb96-41da-8e39-85fb4112f1ca.jpg?v=1780201700","url":"https:\/\/lateknightbooks.com\/products\/9780470503485","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}