{"product_id":"9780470710234","title":"Reagents for Silicon-Mediated Organic Synthesis","description":"\u003ch3\u003eHandbook of Reagents for Organic Synthesis\u003c\/h3\u003e\u003ch1\u003eReagents for Silicon-Mediated Organic Synthesis\u003c\/h1\u003e\u003ch3\u003ePhilip L. Fuchs\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eTechnology \u0026amp; Engineering \/ Industrial Health \u0026amp; Safety\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eOver the last three decades the importance of organosilicon chemistry has greatly increased because it has opened a number of new synthetic strategies. Silicon reagents are usually low-cost, versatile and allow a wide range of reactions. This is the first Handbook to compile essential Silicon containing reagents and makes use of the leading reagent database \u003ci\u003ee-EROS.\u003c\/i\u003e Another hot volume in the series \u003ci\u003eHandbooks of Reagents for Organic Synthesis\u003c\/i\u003e, this is a must-have resource for all synthetic chemists working in drug development and medicinal chemistry.  \u003cp\u003eFor the selection the Editor focussed on three key synthetic approaches with the greatest impact:\u003c\/p\u003e \u003cp\u003e1. Use of silicon as a 'temporary tether' by unifying a reactive pair of functional groups and taking advantage of their template-biased intramolecular cyclization.\u003c\/p\u003e \u003cp\u003e2. The specific use of the silane functionality as a hetero \u003ci\u003et-\u003c\/i\u003ebutyl group, often colloquially referred to as the use of silicon as a 'fat proton'.\u003c\/p\u003e \u003cp\u003e3. The use of the \u003ci\u003eBrook rearrangement\u003c\/i\u003e as an 'anion relay stratagem'.\u003c\/p\u003e \u003cp\u003eA new feature in this Handbook is the reagent finder, an alphabetically organized lookup table arranged by organic functionality and specific structure of the silicon atom to which it is bound.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cstrong\u003ePhilip Fuchs\u003c\/strong\u003e began his career at Purdue in 1973. Since that time, he has graduated an extended family of 55 Ph.D.s. His awards and honors include an Eli Lilly young faculty fellowship (1975), an Alfred P. Sloan fellowship (1977), a Pioneer in Laboratory Robotics award (1986), a Martin teaching award (1991), and being voted by the students as one of Top 10 Teachers in School of Science at Purdue (1991, 1993, 1995, 1996).\u003cbr\u003eFuchs has consulted for Pfizer, and Eli Lilly, served on the editorial board of \u003cem\u003eThe Journal of Organic Chemistry\u003c\/em\u003e, and is currently an executive editor for the \u003cem\u003eElectronic Encyclopedia of Organic Reagents (e-EROS)\u003c\/em\u003e, an online dynamic encyclopedia published by John Wiley \u0026amp; Sons. \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e14 November 2011\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470710234\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e854\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e91.2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44378822082700,"sku":"9780470710234","price":136.76,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470710234.jpg?v=1780109345","url":"https:\/\/lateknightbooks.com\/products\/9780470710234","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}