{"product_id":"9780470855102","title":"Cancer and Inflammation","description":"\u003ch1\u003eCancer and Inflammation\u003c\/h1\u003e \u003ch2\u003eChadwick, Derek J.; Goode, Jamie A.\u003c\/h2\u003e \u003cp\u003eChronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are detected in a range of common cancers, together with the inflammatory cytokines and members of the chemokine ligand\/receptor systems.\u003cbr\u003e \u003cbr\u003e Neutralization or deletion of the gene for some inflammatory cytokines confers resistance to tumour induction and experimental metastasis. Over-expression of such cytokines in tumour cells may enhance malignant potential. Certain chemokines are likely to subvert antitumour immunity by favouring development of ineffective Type 2 responses. Tumour cells may even utilize chemokine receptors in homing to lymph nodes and other organs. Thus, the cells, cytokines and chemokines found in tumours are more likely to contribute to tumour growth, progression and immunosuppression than they are to mount an effective host antitumour response.\u003cbr\u003e \u003cbr\u003e This book draws together contributions from an international group of scientists and clinicians from diverse disciplines, ranging from epidemiology to immunology, cell biology, molecular oncology, molecular medicine and pharmacology to debate these and related issues. Topics covered include the epidemiological links between cancer and inflammation, the parallels between inflammation and cancer, the role of inflammation in cancer, inflammatory genes as risk factors for cancer initiation and progression, inflammation and cancer angiogenesis, and preventative and therapeutic strategies.\u003cbr\u003e \u003cbr\u003e Related Novartis Foundation symposia:\u003cbr\u003e 252 Generation and Effector Functions of Regulatory Lymphocytes\u003cbr\u003e Chair: Jean-François Bach\u003cbr\u003e \u003cbr\u003e 254 Immunoinformatics: Bioinformatic Strategies for Better Understanding of Immune Function\u003cbr\u003e Chair: Hans-Georg Rammensee\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Wiley\u003c\/p\u003e \u003cp\u003ePublication Date: 2004-03-05\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9780470855102\u003c\/p\u003e \u003cp\u003eDOI: \u003c\/p\u003e \u003cp\u003eDimensions: 237.0cm x159.5cm\u003c\/p\u003e \u003cp\u003ePages: 296.0\u003c\/p\u003e ","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44314229997708,"sku":"9780470855102","price":228.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470855102_e5377ea1-f42c-4a9d-9d63-119e8c8165d7.jpg?v=1765320966","url":"https:\/\/lateknightbooks.com\/products\/9780470855102","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}