{"product_id":"9780470972458","title":"Antibacterial Agents Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications","description":"\u003ch1\u003eAntibacterial Agents\u003c\/h1\u003e\u003ch2\u003eChemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications\u003c\/h2\u003e\u003ch3\u003eRosaleen Anderson | Paul W. Groundwater | Adam Todd | Alan Worsley\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Chemistry \/ Industrial \u0026amp; Technical\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eAntibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function.\u003cbr\u003e \u003cbr\u003e \u003ci\u003eAntibacterial Agents\u003c\/i\u003e is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eAgents covered include:\u003c\/b\u003e  \u003cul\u003e \u003cli\u003eagents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents\u003c\/li\u003e \u003cli\u003eagents targeting metabolic processes -  sulfonamide antibacterial agents and trimethoprim\u003c\/li\u003e \u003cli\u003eagents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones\u003c\/li\u003e \u003cli\u003eagents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eAntibacterial Agents\u003c\/i\u003e will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design\/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e \u003cb\u003eProfessor Rosaleen Anderson, \u003c\/b\u003eProfessor of Pharmaceutical Chemistry, Sunderland Pharmacy School, University of Sunderland, UK \u003cp\u003e\u003cb\u003eProfessor Paul Groundwater, \u003c\/b\u003eProfessor of Medicinal Chemistry, Faculty of Pharmacy, The University of Sydney, Australia\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Adam Todd, \u003c\/b\u003eSenior Lecturer in Pharmacy Practice, Sunderland Pharmacy School, University of Sunderland, UK\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDr Alan Worsley, \u003c\/b\u003ePrincipal Lecturer in Pharmacy Practice, Sunderland Pharmacy School, University of Sunderland, UK\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e30 July 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780470972458\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e378\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e29.12\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310950346892,"sku":"9780470972458","price":54.86,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780470972458_eba37936-3502-400d-9573-63d811c4740a.jpg?v=1780141848","url":"https:\/\/lateknightbooks.com\/products\/9780470972458","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}