{"product_id":"9780471405207","title":"LC\/MS Applications in Drug Development","description":"\u003ch3\u003eWiley Series on Mass Spectrometry\u003c\/h3\u003e\u003ch1\u003eLC\/MS Applications in Drug Development\u003c\/h1\u003e\u003ch3\u003eMike S. Lee | Dominic M. Desiderio | Nico M. Nibbering\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Chemistry \/ Industrial \u0026amp; Technical\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eBreakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC\/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC\/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases.\u003cbr\u003e In addition to the thorough technical analysis of this tool, \u003cb\u003e\u003ci\u003eLC\/MS Applications in Drug Development\u003c\/i\u003e\u003c\/b\u003e provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC\/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include:  \u003cul\u003e \u003cli\u003eProteomics\u003c\/li\u003e \u003cli\u003eGlycoprotein Mapping\u003c\/li\u003e \u003cli\u003eNatural Products Dereplication\u003c\/li\u003e \u003cli\u003eLead Identification Screening\u003c\/li\u003e \u003cli\u003eOpen-Access LC\/MS\u003c\/li\u003e \u003cli\u003eIn Vitro Drug Screening\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWritten for both the analytical chemist who uses LC\/MS applications and the pharmaceutical scientist who works with the drugs they produce, \u003cb\u003e\u003ci\u003eLC\/MS Applications in Drug Development\u003c\/i\u003e\u003c\/b\u003e is the premier reference on the subject.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e MIKE S. LEE, PhD, is President of Milestone Development Services, a consulting firm specializing in pharmaceutical analysis and drug development strategies. He lives in Newtown, Pennsylvania.\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e07 March 2002\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Interscience\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9780471405207\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e256\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e17.06\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44315275460748,"sku":"9780471405207","price":184.46,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9780471405207_1e7a2d9c-1160-4a41-bb15-c990827a8a58.jpg?v=1780176528","url":"https:\/\/lateknightbooks.com\/products\/9780471405207","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}