Genotype Phenotype Coupling: Methods and Protocols

Zielonka, Stefan; Krah, Simon

This detailed new edition broadens the scope of the first edition by moving beyond classical display technologies. This book explores methodologies for the generation of natively paired antibody libraries, single cell technologies, alternative scaffolds, and in silico antibody sequence assessments are described. The application of these methods may allow for a generation of improved therapeutics and diagnostic reagents in a shorter time frame. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Details

Published by: Humana

Publication Date: 2023-07-06

Format: Hardcover

ISBN-13: 9781071632789

DOI: 10.1007/978-1-0716-3279-6

Dimensions: 254.0cm x178.0cm

Pages: 408.0