Methods in Molecular Biology: Methods and Protocols

Rani, Sweta; Skalniak, Lukasz

This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical mouse models to study primary and metastatic brain cancer; and methods to generate CAR T-cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Immuno-Model in Cancer: Methods and Protocols is a valuable resource for both new and experienced researchers who want to learn more about this important and developing field.

Details

Published by: Humana

Publication Date: 2025-10-02

Format: Hardcover

ISBN-13: 9781071647332

DOI: 10.1007/978-1-0716-4734-9

Dimensions: 254cm x178cm

Pages: 306