This detailed volume brings together selected clinical perspectives, experimental methods, and therapeutic approaches to the study of the closely intertwined processes of insulin resistance and inflammation. The book examines relevant clinical contexts, including lipedema and childhood cancer survivorship, and presents key methodologies such as electron microscopy, immunohistochemistry, flow cytometry, lipidomics, microbiota profiling, small RNA sequencing, and bioinformatics. It also explores nutritional, exercise-based, psychoeducational, and integrative strategies for the management of insulin resistance. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.

Practical and up-to-date, Insulin Resistance and Inflammation aims to provide clinicians, researchers, laboratory professionals, and students with a practical multidisciplinary resource for investigating insulin resistance and inflammation and translating scientific knowledge into clinical practice.