{"product_id":"9781118488522","title":"Ligand Design in Medicinal Inorganic Chemistry","description":"\u003ch1\u003eLigand Design in Medicinal Inorganic Chemistry\u003c\/h1\u003e\u003ch3\u003eTim Storr\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Life Sciences \/ Biochemistry\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003eIncreasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eLigand Design in Medicinal Inorganic Chemistry\u003c\/i\u003e presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process.\u003c\/p\u003e \u003cp\u003eLigand design is discussed in the following areas:\u003c\/p\u003e \u003cul\u003e \u003cli\u003ePlatinum, Ruthenium, and Gold-containing anticancer agents\u003c\/li\u003e \u003cli\u003eEmissive metal-based optical probes\u003c\/li\u003e \u003cli\u003eMetal-based antimalarial agents\u003c\/li\u003e \u003cli\u003eMetal overload disorders\u003c\/li\u003e \u003cli\u003eModulation of metal-protein interactions in neurodegenerative diseases\u003c\/li\u003e \u003cli\u003ePhotoactivatable metal complexes and their use in biology and medicine\u003c\/li\u003e \u003cli\u003eRadiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents\u003c\/li\u003e \u003cli\u003eCarbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry\u003c\/li\u003e \u003cli\u003eMetalloprotein inhibitors\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eLigand Design in Medicinal Inorganic Chemistry\u003c\/i\u003e provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cstrong\u003eTim Storr, Department of Chemistry, Simon Fraser University, Canada\u003c\/strong\u003e\u003cbr\u003eProfessor Storr has over thirteen years' experience in the field of bioinorganic chemistry and he currently has active research programs in cancer imaging using metal-based agents, and also in the design of metal binding agents for metal overload applications. He teaches a graduate course in bioinorganic chemistry at Simon Fraser University.\u003cbr\u003eProfessor Storr was a member of the organizing committee for the 2011 International Conference on Biological Inorganic Chemistry, and is currently organizing a ligand design symposium at the upcoming 2012 Canadian Chemistry Conference. \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e30 June 2014\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781118488522\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e472\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e36.16\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44381084287116,"sku":"9781118488522","price":168.26,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781118488522.jpg?v=1780207381","url":"https:\/\/lateknightbooks.com\/products\/9781118488522","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}