{"product_id":"9781119114680","title":"Crossover Designs Testing, Estimation, and Sample Size","description":"\u003ch3\u003eStatistics in Practice\u003c\/h3\u003e\u003ch1\u003eCrossover Designs\u003c\/h1\u003e\u003ch2\u003eTesting, Estimation, and Sample Size\u003c\/h2\u003e\u003ch3\u003eKung-Jong Lui\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Clinical Medicine\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eA comprehensive and practical resource for analyses of crossover designs\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFor ethical reasons, it is vital to keep the number of patients in a clinical trial as low as possible.  As evidenced by extensive research publications, crossover design can be a useful and powerful tool to reduce the number of patients needed for a parallel group design in studying treatments for non-curable chronic diseases.  \u003c\/p\u003e \u003cp\u003eThis book introduces commonly-used and well-established statistical tests and estimators in epidemiology that can easily be applied to hypothesis testing and estimation of the relative treatment effect for various types of data scale in crossover designs. Models with distribution-free random effects are assumed and hence most approaches considered here are semi-parametric. The book provides clinicians and biostatisticians with the exact test procedures and exact interval estimators, which are applicable even when the number of patients in a crossover trial is small.  Systematic discussion on sample size determination is also included, which will be a valuable resource for researchers involved in crossover trial design.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eKey features\u003c\/i\u003e:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eProvides exact test procedures and interval estimators, which are especially of use in small-sample cases.\u003c\/li\u003e \u003cli\u003ePresents most test procedures and interval estimators in closed-forms, enabling readers to calculate them by use of a pocket calculator or commonly-used statistical packages.\u003c\/li\u003e \u003cli\u003eEach chapter is self-contained, allowing the book to be used a reference resource. \u003c\/li\u003e \u003cli\u003eUses real-life examples to illustrate the practical use of test procedures and estimators\u003c\/li\u003e \u003cli\u003eProvides extensive exercises to help readers appreciate the underlying theory, learn other relevant test procedures and understand how to calculate the required sample size. \u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eCrossover Designs: Testing, Estimation and Sample Size \u003c\/i\u003ewill be a useful resource for researchers from biostatistics, as well as pharmaceutical and clinical sciences.  It can also be used as a textbook or reference for graduate students studying clinical experiments.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cstrong\u003eKung-Jong Lui\u003c\/strong\u003e, Professor, Department of Mathematics and Statistics, San Diego State University, USA. \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e03 October 2016\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781119114680\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e248\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e15.2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44384076333196,"sku":"9781119114680","price":102.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781119114680_46cd1433-15de-481f-8bbf-fe43ac523b70.jpg?v=1780202420","url":"https:\/\/lateknightbooks.com\/products\/9781119114680","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}