{"product_id":"9781394347858","title":"Essential Pharmacology How Drugs Alter Signaling Pathways in the Body","description":"\u003ch1\u003eEssential Pharmacology\u003c\/h1\u003e\u003ch2\u003eHow Drugs Alter Signaling Pathways in the Body\u003c\/h2\u003e\u003ch3\u003eCarl E. Creutz\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eMaster how drugs modulate the body’s signaling pathways\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eMost medicines work not by creating new physiological processes, but by modulating the body's existing signaling systems, the internal language of hormones, neurotransmitters, and cellular messengers. \u003ci\u003eEssential Pharmacology\u003c\/i\u003e illuminates this central concept while providing accessible yet rigorous mathematical foundations for understanding quantitative pharmacology. \u003c\/p\u003e\n\u003cp\u003eWritten by Carl E. Creutz, Harrison Professor of Medical Teaching in Pharmacology, Emeritus at the University of Virginia, this text guides students through drug absorption, distribution, and biotransformation; clinical pharmacokinetics with practical dosing models; and comprehensive pharmacodynamics including receptor theory, competitive antagonism, and partial agonists. The book explores G-protein coupled receptors, second messenger cascades, and signaling networks that drugs target. By emphasizing general principles, it complements specialized texts in clinical therapeutics, veterinary medicine, toxicology, antimicrobial therapy, and nursing practice. \u003c\/p\u003e\n\u003cp\u003eReaders will find: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eQuantitative pharmacology presented with mathematical rigor yet accessible to students with undergraduate science and mathematics training\u003c\/li\u003e\n\u003cli\u003eComplete drug-receptor interaction models covering competitive antagonists, partial agonists, allosteric mechanisms, and spare receptor theory\u003c\/li\u003e\n\u003cli\u003eClinical pharmacokinetics with single-dose and steady-state models enabling rational drug dosing and therapeutic monitoring\u003c\/li\u003e\n\u003cli\u003eDetailed receptor-effector mechanisms including G-protein signaling, second messengers, and the networks controlling physiological responses\u003c\/li\u003e\n\u003cli\u003eFocus on the unifying principle that modern pharmacology modulates endogenous signaling rather than creating novel body processes\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eEssential Pharmacology\u003c\/i\u003e serves medical, nursing, pharmacy, and other health professional students building theoretical foundations in pharmacology. It equally benefits biomedical researchers, pharmaceutical scientists, and public policy professionals seeking to understand drug development principles and therapeutic limitations.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e \u003cp\u003e\u003cb\u003eCARL E. CREUTZ, PHD,\u003c\/b\u003e is Harrison Professor of Medical Teaching in Pharmacology, Emeritus, at the University of Virginia. where he joined the Department of Pharmacology in 1981.\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e20 April 2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781394347858\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e128\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e7.2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":45169034330252,"sku":"9781394347858","price":57.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781394347858_75d08d3f-ff90-4da9-b860-71f6d86dc436.jpg?v=1780174289","url":"https:\/\/lateknightbooks.com\/products\/9781394347858","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}