Biochemistry of Pulmonary Emphysema

Grassi, C.; Corsico, R.; Travis, J.; Casali, L.; Luisetti, M.

Pulmonary emphysema is a disease which develops because of a localized imbalance between endogenous proteinase inhibitors and proteinases leaking from neurophils during phagocytosis at inflammatory foci within the lung. This volume not only reviews at a biochemical level what is known about the natural inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing proper enzyme-inhibitor balance, including the use of natural or synthetic inhibitors for supplementation or gene therapy.

Details

Published by: Springer

Publication Date: 2014-04-09

Format: Paperback

ISBN-13: 9781447137733

DOI: 10.1007/978-1-4471-3771-9

Dimensions: 244cm x170cm

Pages: 200