Antibodies: Volume 1: Production and Purification

Subramanian, G.

If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including:
-concepts in development of manufacturing strategies,
-importance of antibody fragments,
-application of chromatography method development,
-quality control,
-effect of expression on antibody properties,
-virus removal and safety,
-pharmacokinetics,
-regulatory aspects.

Details

Published by: Springer

Publication Date: 2012-09-18

Format: Paperback

ISBN-10: 9781461347019

ISBN-13: 9781461347019

DOI: 10.1007/978-1-4419-8875-1

Dimensions: 235cm x155cm

Pages: 314