{"product_id":"9781461375715","title":"Alternative Approaches to Human Blood Resources in Clinical Practice: Proceedings of the Twenty-Second International Symposium on Blood Transfusion, Groningen 1997, organized by the Red Cross Blood Bank Noord Nederland","description":"\u003ch1\u003eAlternative Approaches to Human Blood Resources in Clinical Practice: Proceedings of the Twenty-Second International Symposium on Blood Transfusion, Groningen 1997, organized by the Red Cross Blood Bank Noord Nederland\u003c\/h1\u003e \u003ch2\u003eSmit Sibinga, C.Th.; Das, P.C.; Fratantoni, J.C.\u003c\/h2\u003e \u003cp\u003eCurrently blood is a volatile issue. The safety of blood and  the quantification of transfusion risks have been dominant themes that  have stimulated the development of alternative approaches in this  rapidly developing area. In clinical medicine conventional blood and  its components are used in supportive therapies dependent on the  choice of apparent uncritical trigger factors. A compounding factor is  depth of prospective clinical trials for evidence. Such trials in  critical care areas would be of enormous value, not only in recording  adverse effects and under-transfusion, but also indicating the value  of decision analysis and cost-effectiveness in transfusion practice.  Alternative approaches include the use of cytokines, growth factors,  humanised monoclonal antibodies, recombinant plasma factors, and buffy  coat derived natural human interferons. These are being increasingly  implemented in the clinic. Solutions for oxygen transport are being  developed and fibrinogen coated microcapsules are being investigated  for thrombocytopenia. In surgical patients, various crystalloid and  colloid combinations are explored as volume replacements. To avoid  allogeneic transfusions, beneficial blood saving methods include  various strategies, such as autologous deposits, normovolemic  haemodilution and various agents including aprotinin, tranecamic acid,  desmopressin and erythropoietin, but their use in hospital shows  considerable variations. That umbilical cord blood could be a  significant source of allogeneic stem cells in related and unrelated  transplantation is illustrated by the increasing number of cord blood  banks in Europe and elsewhere. Future blood resources are likely to  face several challenges: immediate challenges relate to increased  regulatory and political oversights; intermediate solutions would  offer some improvements in public health and alleviate public fear but  probably not address the economic challenges thrust upon the medical  care system. \u003cbr\u003e  As we approach the year 2000, the major concerns about transfusion  medicine remain its logistics, safety and effectiveness. This theme is  presented in the proceedings of the 22nd International Symposium on  Blood Transfusion, developed in 21 up-to-date topics, collected and  discussed in four sections. \u003cbr\u003e  This book will be of timely value to students, professionals and all  others interested or involved in the field of transfusion medicine,  whether clinical or related.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2012-10-12\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781461375715\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4615-5619-0\u003c\/p\u003e \u003cp\u003eDimensions: 240.0cm x160.0cm\u003c\/p\u003e \u003cp\u003ePages: 260.0\u003c\/p\u003e ","brand":"Springer US","offers":[{"title":"Default Title","offer_id":44358994460812,"sku":"9781461375715","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781461375715_0cd97ee4-397f-46de-8965-7dc2b20523e1.jpg?v=1765470858","url":"https:\/\/lateknightbooks.com\/products\/9781461375715","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}