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Prions and Diseases

Prions and Diseases: Volume 1, Physiology and Pathophysiology

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Prions and Diseases: Volume 1, Physiology and Pathophysiology

Zou, Wen-Quan; Gambetti, Pierluigi

Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer’s disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.

Details

Published by: Springer

Publication Date: 2012-11-13

Format: Hardcover

ISBN-13: 9781461453048

DOI: 10.1007/978-1-4614-5305-5

Dimensions: 235cm x155cm

Pages: 242

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