AAPS Advances in the Pharmaceutical Sciences Series

Timmins, Peter; Pygall, Samuel R.; Melia, Colin D.

This detailed volume addresses key issues and subtle nuances involved in developing hydrophilic matrix tablets as an approach to oral controlled release. It brings together information from more than five decades of research and development on hydrophilic matrix tablets and provides perspective on contemporary issues. Twelve comprehensive chapters explore a variety of topics including polymers (hypromellose, natural polysaccharides and polyethylene oxide) and their utilization in hydrophilic matrices, critical interactions impacting tablet performance, in vitro physical and imaging techniques, and microenvironmental pH control and mixed polymer approaches, among others. In one collective volume, Hydrophilic Matrix Tablets for Oral Controlled Release provides a single source of current knowledge, including sections of previously unpublished data. It is an important resource for industrial and academic scientists investigating and developing these oral controlled release formulations.

Details

Published by: Springer

Publication Date: 2016-09-22

Format: Paperback

ISBN-13: 9781493948277

DOI: 10.1007/978-1-4939-1519-4

Dimensions: 235cm x155cm

Pages: 326