{"product_id":"9781493956395","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eBaumann, Peter\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eRecent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In \"G-Quadruplex DNA: Methods and Protocols\", experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\n\u003cp\u003eAuthoritative and cutting-edge, \"G-Quadruplex DNA: Methods and Protocols \"promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of G-quadruplex DNA.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493956395\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-59745-363-9\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 276\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542837416076,"sku":"9781493956395","price":107.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493956395.jpg?v=1772845342","url":"https:\/\/lateknightbooks.com\/products\/9781493956395","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}