{"product_id":"9781493958221","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eGoodchild, John\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe field of oligonucleotide therapeutics research is ripe with the prospect of new discoveries. In \u003ci\u003eTherapeutic Oligonucleotides: Methods and Protocols\u003c\/i\u003e, a selection of established and emerging methods for the application of oligonucleotides as therapeutics are presented, all providing the tools needed to inspire great changes in the field. Divided into twenty-one chapters, this detailed volume meticulously describes vital protocols for optimizing and improving cell uptake, such as photochemical internalization, modified cell penetrating peptides, antibody conjugates, and nanoparticles. Other chapters address quantitation of RNA therapeutics in cells, assaying gene knockdown, selecting the best target site and synthesis of various modified oligonucleotides. Written in the successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eAuthoritative and easily accessible, \u003ci\u003eTherapeutic Oligonucleotides: Methods and Protocols \u003c\/i\u003eserves as a timely resource for both professionals and novices pursuing research in this exciting and pioneering field.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493958221\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-61779-188-8\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 340\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542866088076,"sku":"9781493958221","price":107.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493958221.jpg?v=1772845836","url":"https:\/\/lateknightbooks.com\/products\/9781493958221","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}