{"product_id":"9781493959440","title":"Methods in Molecular Biology: Methods and Protocols, Second Edition","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols, Second Edition\u003c\/h1\u003e \u003ch2\u003eChames, Patrick\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eMore than ever, antibodies are being recognized as a major drug modality in a variety of diseases, including cancer, autoimmune diseases, infectious diseases, or even neurodegenerative disorders. Over 30 therapeutic antibodies have been approved and novel molecules are entering clinical trials at an average rate of 50 per year and that is predicted to continue well into the future. Notwithstanding the many achievements already made in the field, there is still a lot of room for improvements for these molecules in terms of activity, and a plethora of approaches have been attempted to optimize these molecules. \u003ci\u003eAntibody Engineering: Methods and Protocols, Second Edition\u003c\/i\u003e was compiled to give complete and easy access to a variety of antibody engineering techniques, starting from the creation of antibody repertoires and efficient ways to select binders from these repertoires, to their production in various hosts, their detailed characterization using various well established techniques, and to the modification and optimization of these lead molecules in terms of binding activity, specificity, size, shape, and more. Written in the successful \u003ci\u003eMethods in Molecular Biology™\u003c\/i\u003e series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eAuthoritative and easily accessible, \u003ci\u003eAntibody Engineering: Methods and Protocols, Second Edition\u003c\/i\u003e serves as an invaluable resource for both experts and those new to the field, and most of all as a source of inspiration for the creation of the antibodies of tomorrow. \u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493959440\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-61779-974-7\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 734\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542863073420,"sku":"9781493959440","price":179.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493959440.jpg?v=1772845687","url":"https:\/\/lateknightbooks.com\/products\/9781493959440","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}