{"product_id":"9781493971701","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eGautier, Jean-Charles\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis second edition provides up-to-date chapters and new chapters focusing on the most recent advances in the field of drug safety evaluation. Divided into seven parts, chapters detail specific aspects related to the experimental design of preclinical studies conducted to support the safety of pediatric and combination drugs, necropsy and histopathology evaluation, mass spectrometry imaging, genetic toxicology protocols including the \u003ci\u003ePig-a\u003c\/i\u003e mutation assay, safety pharmacology methods such as automatization of patch-clamp procedures, target safety assessment for investigative toxicology, screening assays for developmental toxicology, and methods to characterize novel translational safety biomarkers like microRNAs. Written in the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls.\u003c\/p\u003e\u003cp\u003eAuthoritative and practical,\u003ci\u003e Drug Safety Evaluation: Methods and Protocols, Second Edition\u003c\/i\u003e aims to ensure successful results in the further study of this vital field.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2017-07-27\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493971701\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-7172-5\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 427\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":46265643401356,"sku":"9781493971701","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493971701.jpg?v=1772846349","url":"https:\/\/lateknightbooks.com\/products\/9781493971701","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}