{"product_id":"9781493983216","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eGalea, Charles A.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eSince the identification of the first matrix metalloprotease (insterstitial collagenase or MMP-1) more than 20 closely related and evolutionarily conserved vertebrate MMPs have been discovered. Chapters in this volume detail methods and protocols on recent advances in the expression and purification of MMPs, biophysical methods such as X-ray crystallography, NMR spectroscopy and small angle X-ray scattering, computational and experimental methods for determining MMP specificity, methods for detecting MMP activity \u003ci\u003ein vitro\u003c\/i\u003e and \u003ci\u003ein vivo\u003c\/i\u003e, and methods for the development and characterization of MMP-based inhibitors as potential therapeutics for the treatment of various diseases. Written in the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\n\n\u003cbr\u003e Authoritative and practical, \u003ci\u003eMatrix Metalloproteases: Methods and Protocols \u003c\/i\u003eaims to ensure successful results in the further study of this vital field. \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-08-07\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781493983216\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-4939-6863-3\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 314\u003c\/p\u003e ","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":46542911963276,"sku":"9781493983216","price":116.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781493983216.jpg?v=1772847272","url":"https:\/\/lateknightbooks.com\/products\/9781493983216","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}