Effects of Genome Structure and Sequence on the Generation of Variation and Evolution, Volume 1267

Caporale, Lynn H.

The structure of DNA varies along its sequence, which can lead to sequence-dependent variations in the fidelity of DNA copying and repair. And because the probability of distinct classes of mutations varies along a DNA sequence, variation that affects fitness will have evolutionary implications, as selection acts on heritable variation.

This Annals volume brings together a broad interdisciplinary group of researchers to explore the impact of increasing understanding of DNA structure, repair, replication, and organization on interrelated subjects ranging from evolution, to dependence of the effect of mutagens on environmental and sequence context, to noncanonical forms of information representation in genomes.

NOTE: Annals volumes are avaialble for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Joun.aspx for more information about becoming a member.

Details

Published by: Wiley-Blackwell

Publication Date: 2012-10-09

Format: Paperback

ISBN-13: 9781573318877

DOI:

Dimensions: 254.0cm x180.3cm

Pages: 252.0