{"product_id":"9781573318921","title":"Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258","description":"\u003ch3\u003eAnnals of the New York Academy of Sciences\u003c\/h3\u003e\u003ch1\u003eBarriers and Channels Formed by Tight Junction Proteins II, Volume 1258\u003c\/h1\u003e\u003ch3\u003eMichael Fromm | Jörg-Dieter Schulzke\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Life Sciences \/ Cell Biology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003eTight junction proteins connect epithelial and endothelial cells and, importantly, form selective barriers and channels for paracellular transportation.  Two types of tight junction proteins—the claudin family (claudins-1 to -27) and the TAMP family (occludin, Marvel-D2, and tricellulin)—can be distinguished molecularly and functionally.  Recent work has focused on delineating the functional significance of differences in selective permeability, for example, by examining the regulatory mechanisms of tight junctions.  This work is of great clinical importance as many inflammatory or infectious diseases are characterized by increased permeability and the manipulation of tight junctions presents a new horizon in the development of novel therapeutics.  The volume \u003ci\u003eBarriers and Channels Formed by Tight Junction Proteins II\u003c\/i\u003e provides a detailed look at the recent advances in our understanding of tight junction regulation and dysregulation.  The papers included focus on three major themes: inflammation and gastrointestinal function; epithelial transport, barrier modulation, and food components; and tight junctions in intestinal and renal epithelia.\u003c\/p\u003e \u003cp\u003eNOTE: Annals volumes are available for sale as individual books or as a journal. For more information on instutional journal subscriptions, please visit \u003ca href=\"http:\/\/ordering.onlinelibrary.wiley.com\/subs.asp?ref=1749-6632\u0026amp;doi=10.111\/(ISSN)1749-6632\"\u003ehttp:\/\/ordering.onlinelibrary.wiley.com\/subs.asp?ref=1749-6632\u0026amp;doi=10.111\/(ISSN)1749-6632\u003c\/a\u003e\u003c\/p\u003e \u003cp\u003eACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (\u003ca href=\"http:\/\/www.nyas.org\"\u003ewww.nyas.org\u003c\/a\u003e). Members of the New York Academy of Science receive full-text access to \u003ci\u003eAnnals\u003c\/i\u003e online and discounts on print volumes. Please visit \u003ca href=\"http:\/\/www.nyas.org\/MemberCenter\/Join.aspx\"\u003ehttp:\/\/www.nyas.org\/MemberCenter\/Join.aspx\u003c\/a\u003e for more information on becoming a member.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003eMichael Fromm is the editor of Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258, published by Wiley. Jörg-Dieter Schulzke is the editor of Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258, published by Wiley. \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e24 July 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-Blackwell\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781573318921\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e15.36\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44310608838796,"sku":"9781573318921","price":75.82,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781573318921.jpg?v=1780166350","url":"https:\/\/lateknightbooks.com\/products\/9781573318921","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}