This volume presents a critical appraisal of the current understanding of the molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors. It places emphasis on exploring cutting-edge findings on the structural properties of receptor sites, mechanisms of receptor expression, chemical agents that differentiate receptor subtypes, and phenotypes displayed by GABA receptor null mice. Chapters in this updated and expanded edition examine such topics as GABA receptor subtypes, trafficking postsynaptic GABA receptors, GABA receptor mutations associated with idiopathic generalized epilepsies and febrile seizures, and GABA receptors as a potential therapeutic target.