{"product_id":"9781607614463","title":"Methods in Molecular Biology: Methods and Protocols, Volume 2: Biological Membrane Models","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols, Volume 2: Biological Membrane Models\u003c\/h1\u003e \u003ch2\u003eWeissig, Volkmar\u003c\/h2\u003e \u003cp\u003eEfforts to describe and model the molecular structure of biological membranes go back to the beginning of the last century. In 1917, Langmuir described membranes as a layer of lipids one molecule thick [1]. Eight years later, Gorter and Grendel concluded from their studies that “the phospholipid molecules that formed the cell membrane were arranged in two layers to form a lipid bilayer” [2]. Danielli and Robertson proposed, in 1935, a model in which the bilayer of lipids is sequestered between two monolayers of unfolded proteins [3], and the currently still accepted fuid mosaic model was proposed by Singer and Nicolson in 1972 [4]. Among those landmarks of biomembrane history, a serendipitous observation made by Alex Bangham during the early 1960s deserves undoubtedly a special place. His fnding that exposure of dry phospholipids to an excess of water gives rise to lamellar structures [5] has opened versatile experimental access to studying the biophysics and biochemistry of biological phospholipid membranes. Although during the following 4 decades biological membrane models have grown in complexity and functionality [6], liposomes are, besides supported bilayers, membrane nanodiscs, and hybrid membranes, still an indisputably important tool for membrane b- physicists and biochemists. In vol. II of this book, the reader will fnd detailed methods for the use of liposomes in studying a variety of biochemical and biophysical membrane phenomena concomitant with chapters describing a great palette of state-of-the-art analytical technologies.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2009-12-23\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781607614463\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-60761-447-0\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 548\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542516060300,"sku":"9781607614463","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781607614463.jpg?v=1772841529","url":"https:\/\/lateknightbooks.com\/products\/9781607614463","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}