Leukemia and Lymphoma: Detection of Minimal Residual Disease

Zipf, Theodore F.; Johnston, Dennis A.

In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for leukemias and lymphomas. They apply reverse transcription PCR (RT-PCR) to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for Non-Hodgkin's Lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute lymphoblastic leukemia (ALL), the evaluation of MRD techniques in clinical trials, and the application of flow cytometry techniques.

Details

Published by: Humana

Publication Date: 2010-11-05

Format: Paperback

ISBN-13: 9781617372797

DOI: 10.1007/978-1-59259-318-7

Dimensions: 229cm x152cm

Pages: 257