Clinical specialists caring for patients with any form of vascular disease must clearly understand the basic scientific rationale for disease pathogenesis. This book presents a cohesive review of the current understanding of the most important areas of clinical science and medicine in vascular disease and identifies areas for research in the future. It reviews the study, pathogenesis, management and treatment of some of the most common vascular diseases. The book includes discussions of approaches to gene therapy and aspects of regenerative medicine plus also physiology and pathogenesis, surgical and pharmacologic treatment, and complications.

It will be a useful reference for basic and clinical scientists, and clinical specialists in vascular surgery, cardiology, angiology, neurology and any discipline in which the vascular system plays a fundamental part in the disease process.

Professor Dame Carol Black DBE, PRCP, President of the Royal College of Physicians, Professor and Head Of Academic and Clinical Department of Rheumatology, The Royal Free Hospital and University College London, UK.

Professor David Abraham PhD, Head of Research, Academic and Clinical Department of Rheumatology, The Royal Free Hospital and University College London, UK.

Dr Gerry Coghlan MD, Consultant Cardiologist, Director of the Pulmonary Hypertension Unit, The Royal Free Hospital, London, UK.

Dr Michael Dashwood, PhD, Senior Lecturer in Biochemistry, University College London, UK.

Dr Christopher Denton, PhD, Senior Lecturer and Consultant Rheumatologist, The Royal Free Hospital and University College London, UK.

Dr Clive Handler MD, Honorary Consultant, Pulmonary Hypertension Unit, The Royal Free Hospital, London, UK.

All the authors are internationally respected and leading clinical and basic scientists and clinicians.