{"product_id":"9781898683391","title":"Tuberous Sclerosis Complex From Basic Science to Clinical Phenotypes","description":"\u003ch3\u003eInternational Review of Child Neurology\u003c\/h3\u003e\u003ch1\u003eTuberous Sclerosis Complex\u003c\/h1\u003e\u003ch2\u003eFrom Basic Science to Clinical Phenotypes\u003c\/h2\u003e\u003ch3\u003ePaolo Curatolo\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Neurology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\"This is clearly the most authoritative and contemporary statement of current knowledge yet published.\" \u003cbr\u003e from the Foreword by H. Sarnat\u003cbr\u003e \u003cp\u003eTuberous sclerosis is the prototype of a category of malformations uniquely characterized by disturbances in cellular differentiation and growth. It presents with a complex association of different neurological phenotypes, including seizures, cognitive impairments and autism. It is important not only because it is a relatively common hereditary neurological disease with high morbidity, but because it has implications in other pathological processes, such as dysplasia and neoplasia, hamartoma formation and other disturbances in morphogenic processes.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003eThis book correlates new genetic data and basic science, covers clinical presentation, reviews the historical background and current diagnostic criteria, and deals with the recent advances in neuropathology, molecular genetics and neurobiology which give a better understanding of the pathogenesis of the disease.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003ePaediatricians and child neurologists will find this book uniquely useful.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e Edited by Paolo Curatolo, Università degli Studi di Roma 'Tor Vergata'\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e10 January 2003\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eMac Keith Press\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9781898683391\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e328\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e29.76\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44377794445452,"sku":"9781898683391","price":69.3,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781898683391.jpg?v=1780152927","url":"https:\/\/lateknightbooks.com\/products\/9781898683391","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}