Acute Neuronal Injury: The Role of Excitotoxic Programmed Cell Death Mechanisms

Fujikawa, Denson G.

An overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death. 

Details

Published by: Springer

Publication Date: 2018-12-14

Format: Paperback

ISBN-13: 9783030084684

DOI: 10.1007/978-3-319-77495-4

Dimensions: 235cm x155cm

Pages: 215