{"product_id":"9783030176358","title":"Spatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R","description":"\u003ch1\u003eSpatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R\u003c\/h1\u003e \u003ch2\u003eSchiesser, William E.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe focus of this book is a detailed discussion of a dual cancer vaccine (CV)-immune checkpoint inhibitor (ICI) mathematical model formulated as a system of partial differential equations (PDEs) defining the spatiotemporal distribution of cells and biochemicals during tumor growth.\u003c\/p\u003e\u003cp\u003eA computer implementation of the model is discussed in detail for the quantitative evaluation of CV-ICI therapy. The coding (programming) consists of a series of routines in R, a quality, open-source scientific computing system that is readily available from the internet. The routines are based on the method of lines (MOL), a general PDE algorithm that can be executed on modest computers within the basic R system. The reader can download and use the routines to confirm the model solutions reported in the book, then experiment with the model by varying the parameters and modifying\/extending the equations, and even studying alternative models with the PDE methodology demonstrated by the CV-ICI model.\u003c\/p\u003e\u003cp\u003e\u003ci\u003eSpatiotemporal Modeling of Cancer Immunotherapy: Partial Differential Equation Analysis in R\u003c\/i\u003e facilitates the use of the model, and more generally, computer- based analysis of cancer immunotherapy mathematical models, as a step toward the development and quantitative evaluation of the immunotherapy approach to the treatment of cancer.\u003c\/p\u003e\u003cp\u003eTo download the R routines, please visit: http:\/\/www.lehigh.edu\/~wes1\/ci_download\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2019-06-17\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030176358\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-19080-4\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 112\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44395069243532,"sku":"9783030176358","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030176358.jpg?v=1776785456","url":"https:\/\/lateknightbooks.com\/products\/9783030176358","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}