{"product_id":"9783030249694","title":"Healthy Ageing and Longevity","description":"\u003ch1\u003eHealthy Ageing and Longevity\u003c\/h1\u003e \u003ch2\u003eMoskalev, Alexey\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging.\u003c\/p\u003e\n\n\u003cp\u003eIn an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function).\u003c\/p\u003e\n\n\u003cp\u003eThe book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. \u003c\/p\u003e\n\n\u003cp\u003eIndividual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging.\u003c\/p\u003e\n\n\u003ci\u003eBiomarkers of Human Aging \u003c\/i\u003eis written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.\u003cp\u003e\u003c\/p\u003e\n\n\u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2019-09-24\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030249694\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-24970-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 421\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":45383444103308,"sku":"9783030249694","price":179.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030249694.jpg?v=1777995661","url":"https:\/\/lateknightbooks.com\/products\/9783030249694","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}