This book provides a comprehensive, state-of-the-art overview of follicular lymphoma. The first section of the text explores the current understanding of the biology and pathogenesis of follicular lymphoma, through reviewing recent changes in the WHO classification of low-grade lymphomas, current diagnostic techniques, and emerging research on the importance of the immune microenvironment. The second section focuses on current treatment for localized disease, advanced stage disease, and transformed follicular lymphomas, and details currently FDA approved regimens and evolving radiation techniques for early stage and advanced disease. The last section of the text presents emerging approaches in targeted, immunologic, and vaccine therapy.