{"product_id":"9783030611231","title":"Statistics for Biology and Health: How to Assess, Address, and Account for Mixtures in Association Studies","description":"\u003ch1\u003eStatistics for Biology and Health: How to Assess, Address, and Account for Mixtures in Association Studies\u003c\/h1\u003e \u003ch2\u003eGordon, Derek; Finch, Stephen J.; Kim, Wonkuk\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eHeterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.\u003c\/p\u003e\n\n\u003cp\u003eIn this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.\u003c\/p\u003e\n\nWe anticipate that this book will be useful to researchers who want to estimate heterogeneity in their data, develop or apply genetic association statistics where heterogeneity exists, and accurately evaluate statistical power and sample size for genetic association through the application of robust experimental design.\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2021-12-18\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030611231\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-61121-7\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 352\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44481765572748,"sku":"9783030611231","price":125.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030611231.jpg?v=1775738022","url":"https:\/\/lateknightbooks.com\/products\/9783030611231","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}