This book gathers the second volume of the proceedings of the 31^st edition of the International Conference on Flexible Automation and Intelligent Manufacturing, FAIM 2022, held on June 19 – 23, 2022, in Detroit, Michigan, USA. Covering four thematic areas including Manufacturing Processes, Machine Tools, Manufacturing Systems, and Enabling Technologies, it highlights advances in micro- and nanoscales processes, additive manufacturing, artificial intelligence and robotic applications, human-robot collaboration, as well as quality control, supply chain, industrial monitoring and management strategies. It also discusses important issues related to sustainability, waste management and remanufacturing. All in all, this book provides academicians, engineers and professionals with extensive information on both scientific and industrial advances in the converging fields of manufacturing, production, and automation.