{"product_id":"9783031440892","title":"Advances in Experimental Medicine and Biology: Clinical Features, Human Genetics and Molecular Pathways","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology: Clinical Features, Human Genetics and Molecular Pathways\u003c\/h1\u003e \u003ch2\u003eRickert-Sperling, Silke; Kelly, Robert G.; Haas, Nikolaus\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis 2nd edition has been extensively updated and provides comprehensive and current insight into congenital heart diseases, from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways.\u003c\/p\u003e\n\u003cp\u003eThe book is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and insights from animal models and pathways. All chapters have been updated and new chapters added on state-of-the-art approaches including stem cells and organoids, cardiac metabolism, single cell transcriptomics and 3D reconstruction of human heart development. The clinical chapters have been extended and include new sections on diagnostic imaging techniques.\u003c\/p\u003e\n\u003cp\u003eTaken together, the book, written by and for clinicians and researchers, provides an integrated and up-to-date resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease.\u003c\/p\u003e\n\u003cp\u003eChapter 11 is available open access under a Creative Commons Attribution 4.0 International License via \u003ca class=\"external-link\" href=\"http:\/\/link.springer.com\/\" target=\"_blank\" rel=\"nofollow noopener\"\u003elink.springer.com\u003c\/a\u003e.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2025-06-19\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783031440892\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-031-44087-8\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 1112\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44309195980940,"sku":"9783031440892","price":269.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783031440892_04a231b1-47e8-4754-af79-a5f313b8460a.jpg?v=1777376556","url":"https:\/\/lateknightbooks.com\/products\/9783031440892","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}