{"product_id":"9783031887710","title":"Ehlers-Danlos\/Hypermobility Syndromes and Other Connective Tissue Disorders Assessments, Diagnostics, and Therapies","description":"\u003ch1\u003eEhlers-Danlos\/Hypermobility Syndromes and Other Connective Tissue Disorders\u003c\/h1\u003e\u003ch2\u003eAssessments, Diagnostics, and Therapies\u003c\/h2\u003e\u003ch3\u003eNicholas L. DePace | Stephen Soloway | Michael Yayac | Joe Colombo\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Rheumatology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cspan style=\"font-family: 'Calibri',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin;\"\u003eThis book covers Ehlers-Danlos and hypermobility syndromes with an emphasis on treatment of the parasympathetic and sympathetic (P\u0026amp;S) nervous system dysfunctions. Unfortunately, most EDS\/HSD patients have been misdiagnosed and misunderstood by providers.  EDS\/HSD is a multisystem, multifaceted disorder that is poorly understood. The P\u0026amp;S manifestations and treatments are also poorly understood throughout the healthcare community.  To this end the authors wish to teach providers and patients alike to reduce the life-long suffering from both the disorder and the marginalization. \u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cspan style=\"font-family: 'Calibri',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin;\"\u003eThere are two aspects of teaching that are required and provided by this book: improved understanding of EDS\/HSD and improved understanding of P\u0026amp;S (autonomic) dysfunction and treatment.  For example, with the autonomic nervous system, more treatment or therapy is never better.  Relief of P\u0026amp;S dysfunction must be low and slow to prevent causing more symptoms from higher doses of medication or polypharmacy.  To this end, stress often sets patients back and both providers and patients alike must have proper expectations set for successfully improving patient outcomes (quality of life and productivity). \u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cspan style=\"font-family: 'Calibri',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin;\"\u003eThe book starts with an introduction to and history of the disorder. Chapter II provides a review of the genetics of collagen, the source of the disorders.  Chapters III through IX detail the various forms of EDS\/HSD and goes into more detail on the more common and more well-known variants of EDS\/HSD. Chapter X discusses structural cardiovascular and pulmonary dysfunction associated with EDS\/HSD.  Chapter XI discusses structural gastrointestinal and urogenital dysfunction associated with EDS\/HSD.  The book ends with Chapter XII, which details the involvement of the P\u0026amp;S nervous systems and how to treat, which also has general application to other chronic disorders.\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cspan style=\"font-family: 'Calibri',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin;\"\u003eThis is an ideal guide for rheumatologists and primary care physicians treating patients with Ehlers-Danlos and hypermobility syndromes, and patients and their loved ones in understanding their disease and disorders and the associated treatments and therapies.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin;\"\u003eDr. DePace is board certified Cardiology, Internal Medicine, Lipidology, with over 45 years of practice. \u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp class=\"elementtoproof\"\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif;\"\u003eDr. Soloway is board certified Rheumatology and Chairman of Rheumatology, Inspira Health Network since 1993, with over 36 years of practice. Dr. Soloway has been treating Ehlers-Danlos Syndrome Hypermobility Spectrum Disorder throughout his entire career. Dr. Soloway recognized that while EDS\/HSD (a genetic disorder of collagen in the connective tissue) has no cure (the geneticists are still working to determine the genetic makeup of EDS\/HSD), the vast majority of symptoms and the individuality of the manifestation of the disorder in patients is due to P\u0026amp;S (autonomic) dysfunction.\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp class=\"elementtoproof\"\u003eDr. Michael Yayac is a resident in Orthopedic Surgery at Inspira Health Network.\u003c\/p\u003e\r\n\u003cp\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif;\"\u003eDr. Colombo is trained in Neurology, with expertise in BioMedical Engineering, Neuroscience, and Autonomic Nervous System medicine (Neurocardiology). He invented the medical technology that non-invasively measures Parasympathetic and Sympathetic Nervous System (P\u0026amp;S) activities independently and simultaneously, as opposed to only total autonomic activity, and has been developing it for clinical practice and research for over 30 years.  He opened the first P\u0026amp;S clinic with Dr. DePace in 2008. \u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; color: #1f497d;\"\u003e \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif; background: yellow;\"\u003eThe\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif;\"\u003e authors have been Professors of Medicine for several institutions and continue to teach clinical medicine in the various practices and hospitals they attend. Dr. Soloway has been referring patients to Drs. DePace and Colombo for nearly ten years.  Based on these referrals and word of mouth referrals from patients, the doctors, to date, have over 3,000 EDS\/HSD patients under care.  Unfortunately, most of these patients have been misdiagnosed and misunderstood for the majority of their lives by other providers and even family members.  EDS\/HSD is a multisystem, multifaceted disorder that is poorly understood and the P\u0026amp;S manifestations and treatments are also poorly understood throughout the healthcare community.  To this end the doctors\/authors wish to teach providers and patients alike, to raise awareness and reduce the life-long suffering that not only the disorder brings but the dismissal and marginalization that the lack of understanding brings to the patients and give hope to restore quality of life and productivity.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e28 September 2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eSpringer Nature Switzerland\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783031887710\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e596\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Springer Nature Switzerland","offers":[{"title":"Default Title","offer_id":63414233104524,"sku":"9783031887710","price":143.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783031887710.tif?v=1792543162","url":"https:\/\/lateknightbooks.com\/products\/9783031887710","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}