This book provides insights in the field of cyber-physical systems (CPS), which tightly integrates computation, networking, and physical processes. It has transformed the technological landscape across sectors such as manufacturing, healthcare, energy, transportation, and defence. However, there is an urgent need to develop and deploy next-generation networking paradigms that can meet stringent requirements for reliability, latency, scalability, and security. This book brings together leading-edge contributions in three major directions: (i) Transmission Control Protocol (TCP) (ii.) Software-Defined Networking (SDN) (iii.) Emerging Technologies. The chapters in this book span theoretical models, experimental designs, protocol innovations, and real-world case studies. Collectively, they provide valuable insights for researchers, practitioners, and students engaged in networking, control systems, embedded computing, and interdisciplinary CPS domains.