This book reports on research concerning methods, modeling, and simulation tools for material science and manufacturing.  It covers emerging materials and composites, advanced machining, and applications in automotive and energy. It also highlights the use of machine learning for analyzing and optimizing the manufacturing process. Gathering the proceedings of the fifth International Conference on Advanced Materials Mechanics and Manufacturing, A3M2025, held on June 13-15, 2025, in Hammamet, Tunisia, and organized by the Laboratory of Mechanics, Modeling, and Manufacturing (LA2MP) of the National School of Engineers of Sfax, this book provides researchers and professionals with a timely snapshot of engineering methods in mechanics, materials and manufacturing. It also highlights important collaborative work between different countries and between industry and universities.