This book constitutes the refereed proceedings of the 8th International Conference on Information Science and Systems, ICISS 2025, held in Oxford, UK, during September 14-16, 2025.

The 21 full papers included in this book were carefully reviewed and selected from 88 submissions. They are organized in topical sections as follows: Modeling and Numerical Calculation of Complex Systems; Intelligent Image Detection, Recognition and Analysis Methods; Intelligent Algorithms and Data Management in Advanced Information Technology; Artificial Intelligence Theory and Innovative Applications; and Information Privacy and Security Based on LLM.