This book addresses how organizations can transform information systems into intelligent decision-making platforms that respond dynamically to change and uncertainty. Readers will discover practical frameworks for leveraging large language models, implementing ESG reporting solutions, creating digital twin environments, and deploying blockchain-based security, all drawn from real-world implementations. The contributions demonstrate how AI, IoT, and big data enable organizations to move beyond traditional information processing toward predictive and autonomous management capabilities. Each chapter provides actionable strategies for digital transformation, from metaverse-based safety training to cryptocurrency optimization and AI-enhanced public health interventions. This book serves as an essential resource for academic researchers exploring information management, intelligent management, digital transformation, and industry professionals implementing AI-driven solutions.