This book constitutes the First UPADI Conference on Artificial Intelligence, UPADI-AI 2026, held in Lima, Peru, during August 25–28, 2026.

The 14 full papers included in this book were carefully reviewed and selected from 59 submissions.They organized in the following topical sections as follows Application of Artificial Intelligence in Energy, Application of Artificial Intelligence in Health,  Application of Artificial Intelligence in Higher Education, Application of Artificial Intelligence in Infrastructure and  Ethics, Responsibility and Equity in Artificial Intelligence.