This two part volume constitutes the refereed proceedings of the 12th International Conference on Information Management, ICIM 2026, held in Oxford, UK, during March 27–29, 2026.

The 69 full papers and 13 short papers were included in these volumes were carefully reviewed and selected from 206 submissions. They are organized into the following topical sections:

Part I: Machine Learning-based Information System Management and Data Analysis Methods; Software and Intelligent Programming Design; Generative AI and Information Retrieval Based on Large Language Models; Intelligent information system and intelligent management based on multimodal data fusion.

Part II: AI-driven enterprise management process design and intelligent decision-making methods; Financial and Business Intelligence Empowered by Artificial Intelligence; AI-based intelligent education management and multimodal learning methods; Smart City Governance System and Public Management Plan; Design of Smart Healthcare Information System and Data-Driven Intelligent Diagnostic Technology.