This volume set constitutes the proceedings of the 25th International Conference on Artificial Intelligence and Soft Computing, ICAISC 2026, held in Zakopane, Poland, during June 14–18, 2026.

The 107 full papers included in this book were carefully reviewed and selected from 175 submissions. The papers cover the following topical sections:

Part I: Neural Networks and Their Applications; Various Problems of Artificial Intelligence; Agent Systems, Robotics and Control; and Bioinformatics, Biometrics and Medical Applications.

Part II: Computer Vision, Image and Speech Analysis; Data Mining; Evolutionary Algorithms and Their Applications; Artificial Intelligence in Modeling and Simulation.