This book presents the best papers from the International Conference on Innovations in Sustainable Agriculture 4.0 (March 26–27, 2026, Stavropol, Russia), offering practical insights into transformative technologies and practices that are shaping the future of sustainable farming. It covers four key thematic areas: digital agricultural techniques, tools, and systems—highlighting data analytics and automation for optimized farm operations; sustainable development of agricultural and food production—focusing on regenerative practices for soil health and food security; economic, ecological, and social systems for human development—examining integrated approaches to enhance rural livelihoods and community resilience; and sustainability in animal husbandry and veterinary practice—addressing innovations that improve animal welfare while minimizing environmental impacts. Designed for researchers, farmers, policymakers, and students, this book provides a multidisciplinary perspective on building a sustainable and resilient food system.