This book reviews the top ten best-selling drugs including two biologic drugs, one peptide drug, and seven small molecule drugs. Each drug is covered by its history, pharmacology, ADME, safety and synthesis/production. The history section of this book offers a panorama view of the particular subject matter. This book reflects the state-of-the-art of today’s drug discovery with the latest references. This book is intended for scientists in both academia and industry working in drug discovery as well as senior undergraduate students and graduate students.

Award-winning author, Dr. Jie Jack Li, has had over 30 years of experience in medicinal chemistry and drug discovery in both big pharma and biotechnology companies including Pfizer and BMS. He also took a four-year sojourn as an associate professor at the University of San Francisco, teaching and researching organic chemistry and medicinal chemistry. Dr. Li has published over 35 books on organic chemistry, medicinal chemistry, and history of drug discovery, 10 of them with Nobel Laureate E.J. Corey. His 2013 book, Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry, won the 2015 Alpha Sigma Nu Book Science Book Award.