This book provides a comprehensive introduction to multiphysics simulation, artificial intelligence (AI), and their integration in modern computational engineering. It presents the mathematical and computational foundations of physics-based simulation and demonstrates how AI can be incorporated into advanced engineering analysis to improve modeling, prediction, and computational efficiency.

The book covers major multiphysics problems, including fluid–structure interaction (FSI), thermal–mechanical coupling, and other coupled physical phenomena, together with numerical techniques such as the finite element method (FEM), finite difference method (FDM), and meshless approaches. These methods are presented in the context of solving complex problems across mechanical, materials, and biomedical engineering.

Building from the fundamentals of neural networks, the book introduces a broad range of modern AI methods, including Physics-Informed Neural Networks (PINNs), Convolutional Neural Networks (CNNs), Bayesian Neural Networks (BNNs), Generative Adversarial Networks (GANs), and Transformers. Particular emphasis is placed on the interaction between physics-based models and data-driven methods and on their practical use in computational engineering.

The book also addresses important aspects of reliable computational modeling, including verification, validation, and uncertainty quantification, and illustrates the presented concepts through practical engineering applications and case studies. By combining mathematical foundations, numerical simulation, multiphysics modeling, and modern AI techniques, the book provides undergraduate and graduate students, researchers, and engineering professionals with a unified framework for understanding and applying AI-enabled computational methods to real-world engineering problems.

Dr. Hamed Hosseinzadeh is a Lecturer in the Department of Mechanical and Industrial Engineering at the University of Wisconsin–Platteville. He is also the Founder, President, and Technology Strategist of Computational Technology Project (CTP) and Manufacturing Technology Project (MTP), where his work focuses on computational engineering, multiphysics simulation, artificial intelligence, digital twins, and advanced engineering technologies. He is also Co-Founder, CEO, and Chief Computational Technology Officer of Computational Medicine LLC. His research and technology development span computational mechanics, physics-based simulation, AI-enabled engineering, additive manufacturing, and emerging computational technologies.