This book constitutes the refereed proceedings of the First International Conference on The AI Spectrum: Bridging Research, Industry & Innovation, AISPECTRUM 2025, held in Coimbatore, India, during December 22–24, 2025.

The 23 full papers and 4 short papers included in this book were carefully reviewed and selected from 311 submissions. They were organized in topical sections as follows: AI Genesis (Origin, Evolution, and Development of AI Technologies); AI Impact (Transforming Industries, Societies, and Workspaces); AI Horizon (Future Trends, Innovations, and the Next Frontiers of AI); and AI Disrupt (Breakthroughs & Cross-Disciplinary Disruptions).